“Is this a Jojo reference?” is a popular rhetorical question used ironically in the online gaming community. This anime series Jojo’s Bizarre Adventure is the longest-running series of comics and is often referenced in other animes and mangas. This image macro is used to respond to pictures that are from this popular series.
The earliest known use of this popular Depression was on September 13, 2009, in an online thread. 4chan’s posted this image in response to an online statement “FUCK YEAH NAGARSUMI.”
A few days following this thread, a popular Jojos Meme Adventure page on Facebook posted this message with the image and quote, “Is this a Jojo reference?” This post received more than 430 reactions and over 50 comments.